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Like Hair, fingernails and
toenails are composed of a hard protein, keratin. Drugs are
incorporated into nails from the blood stream and remain locked in the nail
as it grows. Nails grow in both length and thickness. Drugs enter the nail
from the base as the keratin is formed and via the nail bed that extends
under the full length of nail.

Drugs can be identified
in nail clippings 2-4 weeks following ingestion and can be detected up to 8
months after last usage. Fingernails grow approximately 3-5 mm per month,
toenails grow at a much slower rate of 1 mm per month which means that drugs
can possibly appear in toenail clippings over 1 year after ingestion
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